Nicole Boucheron, PhD
Group leader
Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna
Boucheron Lab
Working group „T cells in health and disease“
The working group for “T cells in health and disease” connects researchers and groups in Austria working on T lymphocytes from both basic and translational perspectives. The working group aims to share knowledge and expertise related to T cell biology and build a network that fosters collaboration. To promote scientific exchange and collaboration, groups interested in T cells meet regularly online and once per year in person at the ÖGAI annual meeting. The “T cells in health and disease” working group covers a broad spectrum of basic and clinical research topics, including basic T cell biology (development, differentiation, signaling, immune surveillance), immunological and inflammatory disorders (autoimmunity, allergy, immunodeficiency, chronic inflammatory conditions, transplant-related immune reactions), diseases (cancer, infectious diseases), T cell engineering and T cell aging. If you would like to participate, please contact the following E-Mail
Speakers of the working group
Shinya Sakaguchi, PhD
Associate Professor
Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna
Sakaguchi Lab
Peter Steinberger, PhD
Associate Professor
Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna
Steinberger Lab
Dietmar Herndler-Brandstetter, PhD
Ap. Professor
Center for Cancer Research, Comprehensive Cancer Center Vienna, Medical University of Vienna
Herndler-Brandstetter Lab
Nicole Boucheron
Nicole Boucheron performed her PhD studies in Biochemistry and Immunology at the University of Lausanne in Switzerland, where she worked in the group of Immanuel Luescher on activation of CD8+ T cells. In 2002, she joined the group of Wilfried Ellmeier at the Institute of Immunology in Vienna as postdoctoral fellow. Her work helped to understand important pathways that regulate CD4+ T-cell differentiation and she also revealed an unexpected plasticity of CD4+ T-cells towards the CD8 lineage. For her work she received the Sanofi Aventis Prize 2014. Since 2018, she established her own research group with a focus on the molecular control of T helper cell activation and differentiation during immune responses and disease. Current projects focus on molecular determinants for the differentiation of murine and human naïve CD4+ T cells into T follicular helper cells in autoimmunity and Th2 effector cells during allergic airway disease. She is particularly interested in how early signaling and endocytic processes intersect with epigenetic and transcriptional regulation to shape fate decisions and disease control in T helper cells. Nicole Boucheron is a mother of two children.
Shinya Sakaguchi
Shinya Sakaguchi is a group leader at the Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology (CePII), Medical University of Vienna. After completing his Master’s degree in Medical Science in 2002 at the University of Tokyo, Japan, he joined the PhD program of Molecular Biology at the University of Vienna, Austria. After completing his PhD, he worked as a Postdoctoral Fellow at the current institution. He was appointed Assistant Professor at the Medical University of Vienna in 2016 and promoted to Associate Professor in 2019. The current main research topic of his group is to understand the molecular mechanisms underlying the differentiation of peripheral CD8+ T cells, particularly focusing on transcriptional and epigenetic regulations of T cell exhaustion. He has received the Karl Landsteiner Prize from the Austrian Society for Allergology and Immunology and the Sanofi Aventis Prize.
Dietmar Herndler-Brandstetter
Dietmar Herndler-Brandstetter performed his PhD studies in Immunology/Biogerontology at the Institute for Biomedical Aging Research in Innsbruck, Austria. As a FLARE Postdoctoral Fellow, he continued his research on human T cell biology and aging in Innsbruck and at the University of Birmingham (UK). In 2011, he joined the Richard A. Flavell lab at Yale University (USA) as an Erwin Schrödinger Postdoctoral Fellow, where he analyzed the plasticity of effector CD8+ T cells and used next-generation humanized mouse models to study cancer immunotherapies. In 2018, he joined the Center for Cancer Research at the Medical University of Vienna, where he is using humanized mouse models and patient-derived colorectal cancers (PDX) to study the immunosuppressive tumor microenvironment and test novel cancer immunotherapies. He was awarded the Karl Landsteiner Prize and in 2025 he was appointed Ap. Professor in the field of Tumor Immunology.
Peter Steinberger
Peter Steinberger has studied Biology in Graz and Vienna and did his PhD at the University of Vienna (1992-1996). Following postdoctoral studies with Carlos Barbas 3rd at The Scripps Research Institute in San Diego, California (1996-1999), he joined the group of Walter Knapp at the Institute of Immunology. Since 2007 he heads the research group “Immune Receptors and T cell activation” at the Institute of Immunology, Medical University of Vienna. His research focuses on cell engineering, the interaction of surface receptors on immune cells with their ligands and the regulation of human T cell responses. His team is engineering cellular tools that can be used to assess T cell receptors and chimeric antigen receptors as well as the contribution of individual receptor-ligand pairs to T cell activation processes.
Activities of the working group – T cell club
from September 2026 on
Where: Online via Zoom. The link will be sent approximately one week before each meeting.
Format: Two speakers per session, each giving a 20-minute talk followed by a 10-minute Q&A.
Date/Confirmed speakers
24.09.2026 (Thu) 16:00–17:00, Wilfried Ellmeier, Johanna Strobl
22.10.2026 (Thu) 16:00–17:00, Clemens Schmitt, Anna Obenauf
26.11.2026 (Thu) 16:00–17:00, Stefano Angiari, Andreas Bergthaler
28.01.2027 (Thu) 16:00–17:00 Michael Bonelli, Joris van der Veeken
25.02.2027 (Thu) 16:00–17:00, Iris Gratz, Tba
The meetings are open to scientists at all career stages (group leaders, postdocs, students, etc.). If you would like to participate, please contact the organizers at the email below. You will receive the information and Zoom link.
Contact: tcellclub@meduniwien.ac.at

